Solano is identified as a major growth center and as a commercial and financial hub of the Province of Nueva Vizcaya. The Central Business District of the municipality is found at Barangay Poblacion North & Poblacion South where majority of the commercial establishments and activities are concentrated and where the 2 lots of Public Market with an area of 1.2 hectares and 2,000 square meters is also located which is owned and operated by the Local Government Unit.  The market is divided into various commercial sections such as dry goods section, meat and fish section. Market is on a daily basis where agricultural products and consumer products coming from different barangays and neighboring municipalities are brought to be sold at the market site at a fair market value.

The existing commercial areas of the municipality are mostly found in the six (6) center barangays (Barangay Osmeña, Poblacion North, Poblacion South, Quezon, Quirino and Roxas) that comprise the Central Business District of the municipality.

As of 2019, there are three thousand five hundred ninety-nine (3,599) line of business were recorded in the Enhanced Tax Revenue Assessment and Collection System (ETRACS).

Inventory of Business Establishments, 2019

Type of Business No. of Establishments
Banking and Finance 95
Contractor 620
Manufacturer 119
Retailer 1,691
Service 973
Wholesaler 101
Total 3,599